1: 96 percent / 1) 0.02N H2SO4; 2) 2N KOH / ethyl acetate; dioxane / 1) reflux, 30 min; 2) reflux, 30 min 2: diethyl ether; methanol View Scheme

potassium hydroxide; sulfuric acid in 1,4-dioxane; ethyl acetate 1) reflux, 30 min; 2) reflux, 30 min;

1: 96 percent / 1) 0.02N H2SO4; 2) 2N KOH / ethyl acetate; dioxane / 1) reflux, 30 min; 2) reflux, 30 min 2: diethyl ether; methanol 3: 98 percent / quinoline, H2 / 5percent Pd/Lindlar / cyclohexane / 0.75 h 4: 95 percent / 2N KOH / methanol View Scheme

1: 96 percent / 1) 0.02N H2SO4; 2) 2N KOH / ethyl acetate; dioxane / 1) reflux, 30 min; 2) reflux, 30 min 2: diethyl ether; methanol 3: 98 percent / quinoline, H2 / 5percent Pd/Lindlar / cyclohexane / 0.75 h View Scheme