7-甲氧基-1-苯并噻吩合成路线 （共 21 条）
反应条件
1: 1.) aq. NaOH / 1.) Ph2O, 100 deg C, 6 h, 2.) H2O, reflux 2: 70 percent / copper bronze / quinoline / 2 h / 210 - 220 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 12 p. 2973 - 2978
反应条件
1: 90 percent / H2O / 8 h / Heating 2: 70 percent / copper bronze / quinoline / 2 h / 210 - 220 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 12 p. 2973 - 2978
反应条件
1: 100 percent / lNaOH / H2O / 1 h / 100 °C 2: 70 percent / copper bronze / quinoline / 2 h / 210 - 220 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 12 p. 2973 - 2978
反应条件
boron trifluoride-methanol 24 h; Ambient temperature; Yield given;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 18 p. 2683 - 2685
参考文献
Eli Lilly and Company
Patent: US6025382 A1, 2000 ;
反应条件
boron tribromide in dichloromethane
Ambient temperature;
参考文献
Rahman, Loay K. A.; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2973 - 2978
反应条件
1: 55 percent / BBr3 / CH2Cl2 / Ambient temperature
2: 87 percent / K2CO3 / butan-2-one / 3 h / Heating
View Scheme
参考文献
Rahman, Loay K. A.; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2973 - 2978
反应条件
1: 55 percent / BBr3 / CH2Cl2 / Ambient temperature
2: 87 percent / K2CO3 / butan-2-one / 3 h / Heating
3: 74 percent / N.N-dimethylaniline / 6 h / Heating
View Scheme
参考文献
Rahman, Loay K. A.; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2973 - 2978
反应条件
bromine in tetrachloromethane
T=0°C; 1.5 h;
参考文献
Rahman, Loay K. A.; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2973 - 2978
反应条件
nitric acid in acetic acid
T=0°C; 1 h;
参考文献
Rahman, Loay K. A.; Scrowston, Richard M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2973 - 2978
