(2E)-1-(2-羟基苯基)-3-苯基-2-丙烯-1-酮合成路线 （共 83 条）
反应条件
1: 85 percent / n-BuLi / diethyl ether / -78 - 20 °C
2: 83 percent / p-TsOH / tetrahydrofuran; H2O / 55 °C
3: 5 percent / PPh3; DEAD / tetrahydrofuran / 0 °C
View Scheme
参考文献
Hodgetts, Kevin J.
Tetrahedron Letters, 2001 , vol. 42, # 22 p. 3763 - 3766
反应条件
1: 93 percent / imidazole / CH2Cl2
2: 82 percent / Me3Al / CH2Cl2
3: 85 percent / n-BuLi / diethyl ether / -78 - 20 °C
4: 83 percent / p-TsOH / tetrahydrofuran; H2O / 55 °C
5: 5 percent / PPh3; DEAD / tetrahydrofuran / 0 °C
View Scheme
参考文献
Hodgetts, Kevin J.
Tetrahedron Letters, 2001 , vol. 42, # 22 p. 3763 - 3766
反应条件
1: 85 percent / n-BuLi / diethyl ether / -78 - 20 °C
2: 83 percent / p-TsOH / tetrahydrofuran; H2O / 55 °C
3: 5 percent / PPh3; DEAD / tetrahydrofuran / 0 °C
View Scheme
参考文献
Hodgetts, Kevin J.
Tetrahedron Letters, 2001 , vol. 42, # 22 p. 3763 - 3766
反应条件
1: 82 percent / Me3Al / CH2Cl2
2: 85 percent / n-BuLi / diethyl ether / -78 - 20 °C
3: 83 percent / p-TsOH / tetrahydrofuran; H2O / 55 °C
4: 5 percent / PPh3; DEAD / tetrahydrofuran / 0 °C
View Scheme
参考文献
Hodgetts, Kevin J.
Tetrahedron Letters, 2001 , vol. 42, # 22 p. 3763 - 3766
反应条件
1: 83 percent / p-TsOH / tetrahydrofuran; H2O / 55 °C
2: 5 percent / PPh3; DEAD / tetrahydrofuran / 0 °C
View Scheme
参考文献
Hodgetts, Kevin J.
Tetrahedron Letters, 2001 , vol. 42, # 22 p. 3763 - 3766
反应条件
1: 10 percent NaOH / ethanol
2: H3O(1+) / 20 °C
View Scheme
参考文献
Manna, Fedele; Chimenti, Franco; Bolasco, Adriana; Bizzarri, Bruna; Botta, Maurizio; Tafi, Andrea; Filippelli, Amelia; Rossi, Settimio
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 16 p. 1883 - 1885
反应条件
1: 92 percent / toluene / 120 h / 120 °C
2: tetrahydrofuran / 8 h / 40 °C
3: 15 percent / 1M KOH / 96 h / Ambient temperature
View Scheme
参考文献
Chiacchio, Ugo; Casuscelli, Franco; Corsaro, Antonino; Rescifina, Antonio; Romeo, Giovannni; Uccella, Nicola
Tetrahedron, 1994 , vol. 50, # 22 p. 6671 - 6680
反应条件
1: 92 percent / toluene / 120 h / 120 °C
2: tetrahydrofuran / 8 h / 40 °C
3: 15 percent / 1M KOH / 96 h / Ambient temperature
View Scheme
参考文献
Chiacchio, Ugo; Casuscelli, Franco; Corsaro, Antonino; Rescifina, Antonio; Romeo, Giovannni; Uccella, Nicola
Tetrahedron, 1994 , vol. 50, # 22 p. 6671 - 6680
反应条件
in benzene
0.333333 h; Ambient temperature;
参考文献
Patonay, Tamas; Patonay-Peli, Erzsebet; Litkei, Gyoergy
Tetrahedron, 1987 , vol. 43, # 8 p. 1827 - 1834
反应条件
1: 86 percent / Pd(PPh3)2Cl2; CuI; Et3N / dimethylformamide / 24 h / 20 °C
2: 73 percent / p-toluenesulfonic acid / benzene / 24 h / 20 °C
View Scheme
参考文献
De, Mahuya; Majumdar, Dyuti P.; Kundu, Nitya G.
Journal of the Indian Chemical Society, 1999 , vol. 76, # 11-12 p. 665 - 674
