3,5-二苯基-1,2,4-恶二唑合成路线 （共 159 条）
反应条件
boron trifluoride diethyl etherate; 4-chloro-benzoyl chloride in N,N-dimethyl acetamide
16 h; Ambient temperature;
参考文献
Harada; Kaji; Zen
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 11 p. 3296 - 3303
反应条件
in xylene
0.5 h; Heating;
参考文献
Plenkiewicz, Jan; Zdrojewski, Tadeusz
Bulletin des Societes Chimiques Belges, 1987 , vol. 96, # 9 p. 675 - 710
Title/Abstract Full Text Show Details
Plenkiewicz, Jan; Zdrojewski, Tadeusz
Bulletin des Societes Chimiques Belges, 1981 , vol. 90, # 2 p. 193 - 194
反应条件
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
T=191°C; 0.0333333 h; microwave irradiation;
参考文献
Evans, Marc D.; Ring, Jessica; Schoen, Adam; Bell, Andrew; Edwards, Paul; Berthelot, Didier; Nicewonger, Robb; Baldino, Carmen M.
Tetrahedron Letters, 2003 , vol. 44, # 52 p. 9337 - 9341
反应条件
T=150°C; 0.05 h; microwave irradiation;
参考文献
Adib, Mehdi; Jahromi, Amin Haghighat; Tavoosi, Narjes; Mahdavi, Mohammad; Bijanzadeh, Hamid Reza
Tetrahedron Letters, 2006 , vol. 47, # 17 p. 2965 - 2967
反应条件
1: triethylamine / diethyl ether / 6 h / 0 - 20 °C
2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dimethyl sulfoxide / 0.3 h / 100 °C
View Scheme
参考文献
Wang, Yi-Feng; Zhang, Feng-Lian; Chiba, Shunsuke
Organic Letters, 2013 , vol. 15, # 11 p. 2842 - 2845
反应条件
1: hydroxylamine hydrochloride; pyridine / dichloromethane / 20 h / 20 °C / |Inert atmosphere
2: hexafluoroisopropyl alcohol; Oxonereg;; 3,5-dimethylphenyl iodide / methanol; water / 24 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Yoshimura, Akira; Middleton, Kyle R.; Todora, Anthony D.; Kastern, Brent J.; Koski, Steven R.; Maskaev, Andrey V.; Zhdankin, Viktor V.
Organic Letters, 2013 , vol. 15, # 15 p. 4010 - 4013
反应条件
diethyl ether; phosphorus pentabromide
参考文献
Guenther
Chemische Berichte, 1888 , vol. 21, p. 517
Justus Liebigs Annalen der Chemie, 1889 , vol. 252, p. 46,48
反应条件
T=210°C; 0.0833333 h;
参考文献
Smith, Richard F.; Coffman, Karen J.; Geer, Susan M.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 69 - 71
反应条件
in acetonitrile
T=20°C; electrolysis (Pt anode, 1.5 V, 0.2 N NaClO4); Further byproducts given;
参考文献
Petrosyan, V. A.; Niyazymbetov, M. E.; Ul'yanova, E. V.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 3.2 p. 546 - 550
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 3 p. 625 - 629
反应条件
triethylamine in methanol
T=25°C; 48 h;
参考文献
Quadrelli, Paolo; Invernizzi, Anna Gamba; Falzoni, Mario; Caramella, Pierluigi
Tetrahedron, 1997 , vol. 53, # 5 p. 1787 - 1796
