3,5-二苯基-1,2,4-恶二唑合成路线 （共 159 条）
反应条件
1: triethylamine / methanol / 48 h / Ambient temperature
2: 62 percent / benzhydroximoyl chloride, 9,10-dimethylanthracene, triethylamine / methanol / 48 h / Ambient temperature; other reagents: trimethyl phosphite, p-chlorobenzhydroximoyl chloride
View Scheme
参考文献
Quadrelli, Paolo; Invernizzi, Anna Gamba; Falzoni, Mario; Caramella, Pierluigi
Tetrahedron, 1997 , vol. 53, # 5 p. 1787 - 1796
反应条件
1: triethylamine / methanol / 48 h / Ambient temperature
2: 62 percent / benzhydroximoyl chloride, 9,10-dimethylanthracene, triethylamine / methanol / 48 h / Ambient temperature; other reagents: trimethyl phosphite, p-chlorobenzhydroximoyl chloride
View Scheme
参考文献
Quadrelli, Paolo; Invernizzi, Anna Gamba; Falzoni, Mario; Caramella, Pierluigi
Tetrahedron, 1997 , vol. 53, # 5 p. 1787 - 1796
反应条件
1: 70 percent / diethyl ether / 48 h / Ambient temperature
2: triethylamine / methanol / 48 h / Ambient temperature
3: 62 percent / benzhydroximoyl chloride, 9,10-dimethylanthracene, triethylamine / methanol / 48 h / Ambient temperature; other reagents: trimethyl phosphite, p-chlorobenzhydroximoyl chloride
View Scheme
参考文献
Quadrelli, Paolo; Invernizzi, Anna Gamba; Falzoni, Mario; Caramella, Pierluigi
Tetrahedron, 1997 , vol. 53, # 5 p. 1787 - 1796
反应条件
1: 62 percent / diethyl ether / 48 h / Ambient temperature
2: triethylamine / methanol / 48 h / Ambient temperature
3: 62 percent / benzhydroximoyl chloride, 9,10-dimethylanthracene, triethylamine / methanol / 48 h / Ambient temperature; other reagents: trimethyl phosphite, p-chlorobenzhydroximoyl chloride
View Scheme
参考文献
Quadrelli, Paolo; Invernizzi, Anna Gamba; Falzoni, Mario; Caramella, Pierluigi
Tetrahedron, 1997 , vol. 53, # 5 p. 1787 - 1796
反应条件
triethylamine in dichloromethane
benzene, var. conc. of reagent;
参考文献
Caramella, P.; Corsaro, A.; Compagnini, A.; Albini, Marinone F.
Tetrahedron Letters, 1983 , vol. 24, # 40 p. 4377 - 4380
反应条件
in methanol
Irradiation;
参考文献
Quadrelli; Mella; Caramella
Tetrahedron Letters, 1999 , vol. 40, # 4 p. 797 - 800
反应条件
1: 87 percent / 70percent perchloric acid / acetic anhydride / 0.17 h / Ambient temperature
2: 71 percent / NH2OH*HCl, 5M NaOH / 2 h / Ambient temperature
View Scheme
参考文献
Shibuya, Isao
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 11 p. 3369 - 3370
反应条件
1: 74 percent / CHCl3 / 2 h / Ambient temperature
2: sodium hydride / Variation of temperature, and solvents
View Scheme
参考文献
Ooi, Ngan Sim; Wilson, David A.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1792 - 1799
反应条件
1: 1)magnesium / 1) ether, 2) -36 deg C to -40 deg C
2: 83 percent / hydroxylamine hydrochloride, sodium acetate trihydrate / ethanol; H2O / Heating
View Scheme
参考文献
Whitfield, Lawrence L.; Papadopoulos, Eleftherios P.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1197 - 1201
反应条件
1: 1)magnesium / 1) ether, 2) -36 deg C to -40 deg C
2: 83 percent / hydroxylamine hydrochloride, sodium acetate trihydrate / ethanol; H2O / Heating
View Scheme
参考文献
Whitfield, Lawrence L.; Papadopoulos, Eleftherios P.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1197 - 1201
