1,4,5,8-四甲氧基萘-2-甲醛合成路线 （共 21 条）
反应条件
1: 58 percent / Br2 / CCl4 / 0.5 h / 70 °C
2: 84 percent / CuI / dimethylformamide; methanol / 30 h / Heating
3: 99 percent / POCl3 / CHCl3 / 6 h / Heating
View Scheme
参考文献
Terada; Tanoue; Hatada; Sakamoto
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 1 p. 205 - 213
反应条件
1: 78 percent / NaOH / methanol / 3 h / Heating
2: 58 percent / Br2 / CCl4 / 1 h / 73 - 74 °C
3: 84 percent / CuI / dimethylformamide; methanol / 30 h / Heating
4: 99 percent / POCl3 / CHCl3 / 10 h / Heating
View Scheme
参考文献
Terada, Akira; Tanoue, Yasuhiro; Hatada, Akira; Sakamoto, Hiroshi
Journal of the Chemical Society, Chemical Communications, 1983 , # 18 p. 987 - 988
反应条件
1: 96 percent / tetrahydrofuran / 3 h / Ambient temperature
2: 1.) 60percent NaH, 2.) p-toluenesulfonic acid monohydrate / 1.) THF, r.t., overnight, 2.) acetone, 0-5 deg C, 3 h
3: 86 percent / diethyl ether; tetrahydrofuran / 3 h / Ambient temperature
4: 104 mg / SOCl2 / pyridine / 17 h / 0 - 5 °C
5: 5 percent / BBr3 / CH2Cl2 / 2 h / -70 °C
View Scheme
参考文献
Novikov, V. L.; Balaneva, N. N.; Moiseenkov, A. M.; Elyakov, G. B.
Bull. Russ. Acad. Sci. Div. Chem. Sci. (Engl. Transl.), 1992 , vol. 41, # 8.2 p. 1901 - 1910,1485 - 1494
反应条件
1: 99 percent / tetrahydrofuran; diethyl ether / 1 h / Ambient temperature
2: 63 percent / activated manganese dioxide / benzene / 15 h / Heating
3: 3 percent / (NH4)2Ce(NO3)6 / H2O; acetonitrile / 0.5 h / Ambient temperature
View Scheme
参考文献
Cui, Jia-Hua; Zhou, Wen; Li, Shao-Shun
Journal of Chemical Research, 2012 , vol. 36, # 5 p. 264 - 265
反应条件
1: 95 percent / tetrahydrofuran / 3 h / Ambient temperature
2: 52 percent / cerium(IV) ammonium nitrate / acetonitrile; H2O / 0.5 h / 10 - 20 °C
View Scheme
参考文献
Terada, Akira; Tanoue, Yasuhiro; Hatada, Akira; Sakamoto, Hiroshi
Journal of the Chemical Society, Chemical Communications, 1983 , # 18 p. 987 - 988
反应条件
1: 96 percent / tetrahydrofuran / 3 h / Ambient temperature
2: 87 percent / p-toluenesulfonic acid monohydrate / acetone / 3 h / 0 - 5 °C
3: 86 percent / diethyl ether; tetrahydrofuran / 3 h / Ambient temperature
View Scheme
参考文献
Terada; Tanoue; Hatada; Sakamoto
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 1 p. 205 - 213
反应条件
Yield given. Multistep reaction;
参考文献
Terada, Akira; Tanoue, Yasuhiro; Hatada, Akira; Sakamoto, Hiroshi
Journal of the Chemical Society, Chemical Communications, 1983 , # 18 p. 987 - 988
反应条件
1: 96 percent / tetrahydrofuran / 3 h / Ambient temperature
2: 87 percent / p-toluenesulfonic acid monohydrate / acetone / 3 h / 0 - 5 °C
3: 86 percent / diethyl ether; tetrahydrofuran / 3 h / Ambient temperature
4: 70 percent / cerium(IV) ammonium nitrate / CHCl3; acetonitrile; H2O / 0.17 h / Ambient temperature
View Scheme
参考文献
Terada, Akira; Tanoue, Yasuhiro; Hatada, Akira; Sakamoto, Hiroshi
Journal of the Chemical Society, Chemical Communications, 1983 , # 18 p. 987 - 988
反应条件
1: 96 percent / tetrahydrofuran / 3 h / Ambient temperature
2: 87 percent / p-toluenesulfonic acid monohydrate / acetone / 3 h / 0 - 5 °C
3: 86 percent / diethyl ether; tetrahydrofuran / 3 h / Ambient temperature
4: 70 percent / cerium(IV) ammonium nitrate / CHCl3; acetonitrile; H2O / 0.17 h / Ambient temperature
5: 27 percent / AgO, 40percent HNO3 / acetone / 0.17 h / Ambient temperature
View Scheme
参考文献
Terada, Akira; Tanoue, Yasuhiro; Hatada, Akira; Sakamoto, Hiroshi
Journal of the Chemical Society, Chemical Communications, 1983 , # 18 p. 987 - 988
反应条件
1: 96 percent / tetrahydrofuran / 3 h / Ambient temperature
2: 87 percent / p-toluenesulfonic acid monohydrate / acetone / 3 h / 0 - 5 °C
View Scheme
参考文献
Terada; Tanoue; Hatada; Sakamoto
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 1 p. 205 - 213
