4-氯磺酰基-2,3-二氢-1H-茚-2-羧酸甲酯合成路线 (共 2 条)
反应条件
1: With hydrogenchloride; chlorine; sodium nitrite in water; acetonitrile
T=-5 - 0°C; 0.333333 h; Ice-salt bath;
2: With potassium thioxanthate in water; acetonitrile
T=55°C; 0.5 h;
3: With chlorine in tetrachloromethane; water
T=3 - 10°C;
参考文献
KALYPSYS, INC.
Patent: US2007/249519 A1, 2007 ;
Location in patent: Page/Page column 14 ;
反应条件
1: With hydrogenchloride; sodium nitrite in water; acetonitrile
T=-10 - 0°C;
2: With potassium ethylxanthate in water; acetonitrile
T=60°C;
3: With water; chlorine in dichloromethane
T=5°C; Product distribution / selectivity;
参考文献
KALYAPSYS, INC.
Patent: US2007/93504 A1, 2007 ;
Location in patent: Page/Page column 15 ;