1: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 4 h; 2: With triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane T=0 - 20°C; Inert atmosphere;

1: PCl5 2: diethyl ether View Scheme

in diethyl ether

water; ammonium chloride in hexane in sealed evacuated ampule; soln. of Et3GeLi added to soln. of amide at-40°C; stirred at the same temp. for 3 h; hydrolyzed with satd. NH4Cl soln.; dried; isolated by fractionation of the dried org. part ; GLC; mass-spectrometry; elem. anal.;

water; ammonium chloride in hexane in sealed evacuated ampule; soln. of Et3GeLi added to soln. of amide at-40°C; stirred at the same temp. for 3 h; hydrolyzed with satd. NH4Cl soln.; dried; isolated by fractionation of the dried org. part ; GLC; mass-spectrometry; elem. anal.;