1-(3-氯苯基)-5-甲基-1H-1,2,3-噻唑-4-羧酸合成路线 （共 4 条）
反应条件
1: With sodium ethanolate in ethanol
Cycloaddition;
2: With sodium hydroxide in water
Hydrolysis;
参考文献
Sun, Xiao-Wen; Zhang, Yan; Zhang, Zi-Yi; Wang, Qin; Wang, Shu-Fang
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 3 p. 380 - 383
反应条件
1.1: NaNO2; aq. HCl / 0 - 5 °C
1.2: NaN3
2.1: EtONa / ethanol
View Scheme
参考文献
Dong, Heng-Shan; Wang, Bin
Journal of the Chinese Chemical Society, 2005 , vol. 52, # 1 p. 103 - 108
反应条件
1: sodium ethoxide / ethanol
2: sodium hydroxide / H2O
View Scheme
参考文献
Sun, Xiao-Wen; Xu, Peng-Fei; Zhang, Zi-Yi
Magnetic Resonance in Chemistry, 1998 , vol. 36, # 6 p. 459 - 460
反应条件
thionyl chloride
T=70°C; 8 h;
参考文献
Shen; Chen; Wu; Dong
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 4 p. 781 - 786
