5-(对甲苯)异噁唑-3-羧酸乙酯合成路线 （共 10 条）
反应条件
hydroxylamine hydrochloride in ethanol 2 h; Reflux;
参考文献
Andrzejak, Virginie; Muccioli, Giulio G.; Body-Malapel, Mathilde; El Bakali, Jamal; Djouina, Madjid; Renault, Nicolas; Chavatte, Philippe; Desreumaux, Pierre; Lambert, Didier M.; Millet, Regis
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 12 p. 3777 - 3786
反应条件
polyethylene glycol-400 in water T=90°C; 5 h; Green chemistry;
参考文献
Chary, R. Gangadhara; Reddy, G. Rajeshwar; Ganesh; Prasad, K. Vara; Raghunadh, Akula; Krishna; Mukherjee, Soumita; Pal, Manojit
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 1 p. 160 - 164
反应条件
trifluoroacetic acid; sodium nitrite T=20°C;
参考文献
Kadzhaeva; Trofimova; Fedotov; Potekhin; Gazzaeva; Mochalov; Zefirov
Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 5 p. 595 - 605
反应条件
hydroxylamine hydrochloride in ethanol 1 h; Heating;
参考文献
Synthesis, , # 15 p. 2325 - 2330
反应条件
1.1: NaH / toluene / 45 - 50 °C 1.2: toluene / 1.5 h / Heating 2.1: NH2OH*HCl / ethanol / 1 h / Heating View Scheme
参考文献
Synthesis, , # 15 p. 2325 - 2330
反应条件
trifluoroacetic acid; sodium nitrite T=20°C;
参考文献
Chemistry of Heterocyclic Compounds, , vol. 45, # 5 p. 595 - 605
反应条件
1: With sodium hydroxide in ethanol T=20°C; 24 h; 2: With hydrogenchloride in water pH=2;
参考文献
Andrzejak, Virginie; Muccioli, Giulio G.; Body-Malapel, Mathilde; El Bakali, Jamal; Djouina, Madjid; Renault, Nicolas; Chavatte, Philippe; Desreumaux, Pierre; Lambert, Didier M.; Millet, Regis
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 12 p. 3777 - 3786
反应条件
lithium aluminium tetrahydride in diethyl ether T=40°C; 0.5 h;
参考文献
Akbarzadeh, Tahmineh; Rafinejad, Ali; Mollaghasem, Javad Malekian; Safavi, Maliheh; Fallah-Tafti, Asal; Pordeli, Mahboobeh; Ardestani, Sussan Kabudanian; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2012 , vol. 345, # 5 p. 386 - 392
反应条件
1: LiAlH4 / diethyl ether / 0.5 h / 40 °C 2: PCC / CH2Cl2 / 5 h / 20 °C View Scheme
参考文献
Akbarzadeh, Tahmineh; Rafinejad, Ali; Mollaghasem, Javad Malekian; Safavi, Maliheh; Fallah-Tafti, Asal; Pordeli, Mahboobeh; Ardestani, Sussan Kabudanian; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2012 , vol. 345, # 5 p. 386 - 392
反应条件
hydrazine hydrate in water; isopropyl alcohol
参考文献
Gardner,T.S. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1514 - 1518
