1.1: 86 percent / NaH / tetrahydrofuran / 3 h / 60 °C 2.1: 70 percent / K2CO3; Bu4NHSO4 / tetrahydrofuran / 20 °C 3.1: 81 percent / aq. NaCl / dimethylsulfoxide / 135 - 140 °C 4.1: 87 percent / methanol / 20 °C 5.1: NaOH / propan-2-ol / Heating 5.2: 73 percent / Et3SiH / trifluoroacetic acid / 2 h / 0 - 20 °C 6.1: 68 percent / aq. NaIO4 / methanol / 2 h / 0 °C View Scheme

1.1: 70 percent / K2CO3; Bu4NHSO4 / tetrahydrofuran / 20 °C 2.1: 81 percent / aq. NaCl / dimethylsulfoxide / 135 - 140 °C 3.1: 87 percent / methanol / 20 °C 4.1: NaOH / propan-2-ol / Heating 4.2: 73 percent / Et3SiH / trifluoroacetic acid / 2 h / 0 - 20 °C 5.1: 68 percent / aq. NaIO4 / methanol / 2 h / 0 °C View Scheme