反应条件
1: 1.) LDA / 1.) THF, hexane, -78 deg C, 30 min., 2.) THF, -78 to 20 deg C
2: 89 percent / H2, NaBH4, Ni(OAc)2*4H2O, 0.1M NaOH, 1,2-diaminoethane / ethanol / 17 h
3: 12 percent / trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature
View Scheme
参考文献
Klaver, Wim J.; Hiemstra, Henk; Speckamp, W. Nico
Tetrahedron, 1988 , vol. 44, # 21 p. 6729 - 6738
