反应条件
1: 90 percent / NaBH4, acid
2: 1.) LDA / 1.) THF, -78 deg C, 2.) -78 deg C, 30 min, 3.) -78 -> 0 deg C, 2h
3: 97 percent
4: HCO2H / 1 h / Ambient temperature
View Scheme
参考文献
Hiemstra, Henk; Klaver, Wim J.; Speckamp, W. Nico
Journal of Organic Chemistry, 1984 , vol. 49, # 6 p. 1149 - 1151
