Meyer, Michael D.; Hancock, Arthur A.; Tietje, Karin; Sippy, Kevin B.; Prasad, Rajnandan; Stout, David M.; Arendsen, David L.; Donner, B. Greg; Carroll, William A.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 7 p. 1049 - 1062
1: PPA / 0.5 h / 60 °C / Inert atmosphere
2: boron trifluoride diethyl etherate / toluene / 3 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Bonner, Lisa A.; Laban, Uros; Chemel, Benjamin R.; Juncosa, Jose I.; Lill, Markus A.; Watts, Val J.; Nichols, David E.
ChemMedChem, 2011 , vol. 6, # 6 p. 1024 - 1040
1: triethylamine; zinc(II) chloride / dichloromethane / 96 h / Inert atmosphere; Reflux
2: 6 h / 180 °C / Inert atmosphere
3: palladium 10 on activated carbon; hydrogen / ethanol / 2 h / 1520.1 Torr
4: PPA / 0.5 h / 60 °C / Inert atmosphere
5: boron trifluoride diethyl etherate / toluene / 3 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Bonner, Lisa A.; Laban, Uros; Chemel, Benjamin R.; Juncosa, Jose I.; Lill, Markus A.; Watts, Val J.; Nichols, David E.
ChemMedChem, 2011 , vol. 6, # 6 p. 1024 - 1040
