1,3-二丙基-8-p-硫化苯基黄嘌呤合成路线 （共 5 条）
反应条件
sodium hydroxide T=70°C; 0.0833333 h; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 4 p. 487 - 492
反应条件
1: 75 percent / NaNO2, 42percent acetic acid / H2O / 0.25 h / pH 3 2: 83 percent / NaS2O4 / H2O 3: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / 1 h / Ambient temperature 4: 2.5N NaOH / 0.08 h / 70 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 4 p. 487 - 492
反应条件
1: 83 percent / NaS2O4 / H2O 2: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / 1 h / Ambient temperature 3: 2.5N NaOH / 0.08 h / 70 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 4 p. 487 - 492
反应条件
1: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / 1 h / Ambient temperature 2: 2.5N NaOH / 0.08 h / 70 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 4 p. 487 - 492
反应条件
1: SOCl2 / dimethylformamide / 0 - 20 °C
2: dimethylformamide / Ambient temperature
View Scheme
参考文献
Hamilton, Harriet W.; Ortwine, Daniel F.; Worth, Donald F.; Badger, Edward W.; Bristol, James A.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1071 - 1079
