5-溴-2,3-二氨基吡嗪合成路线 (共 4 条)
反应条件
ammonium hydroxide in water T=110°C; 16 h; sealed tube;
参考文献
de Vicente Fidalgo, Javier; Hermann, Johannes Cornelius; Lemoine, Remy; Li, Hongju; Lovey, Allen John; Sjogren, Eric Brian; Soth, Michael
Patent: US2011/59118 A1, 2011 ;
Location in patent: Page/Page column 81-82 ;
反应条件
in ethanol T=20°C; 16 h;
参考文献
Barlin; Ireland
Australian Journal of Chemistry, 1984 , vol. 37, # 5 p. 1057 - 1064
反应条件
in methanol; water; acetic acid
T=50°C; 4 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/39325 A2, 2006 ;
Location in patent: Page/Page column 45 ;
WO 2006/039325 A2
参考文献
Barlin; Ireland
Australian Journal of Chemistry, 1984 , vol. 37, # 5 p. 1057 - 1064