[4-(1H-吡唑-1-基)苯基]硼酸合成路线 (共 2 条)
反应条件
1: 1-(4'-bromophenyl)-1H-pyrazole With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: boric acid trimethyl ester in tetrahydrofuran; hexane T=-78°C; 3: With water; ammonium chloride in tetrahydrofuran; hexane
参考文献
EP1852439 A1, ;
Page/Page column 33 ;
反应条件
1: With n-butyllithium in tetrahydrofuran T=-78 - 20°C; 18 h; 2: With hydrogenchloride; water in tetrahydrofuran 1 h;
参考文献
WO2008/421 A2, ;
Page/Page column 9 ;
WO 2008/000421 A2