1-乙基-2-甲基-4-硝基咪唑合成路线 （共 4 条）
反应条件
nitric acid; acetic acid; potassium iodide T=115 - 120°C; 4 h;
参考文献
Rao; Singh
Synthetic Communications, 1994 , vol. 24, # 3 p. 353 - 366
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=110 - 120°C; 3 h;
参考文献
Bhujanga Rao; Gundu Rao; Sing
Synthetic Communications, 1991 , vol. 21, # 3 p. 427 - 433
反应条件
acetic acid in N,N-dimethyl-formamide
T=80 - 140°C; 10 h; no temperature effects (80 - 140 deg C); regioselective alkylation (5-nitro-isomer); Product distributionMechanism;
参考文献
Rao, A. K. S. Bhujanga; Rao, C. Gundu; Singh, B. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 17 p. 2399 - 2402
反应条件
acetic acid in N,N-dimethyl-formamide
T=80 - 140°C; 10 h; no temperature effects (80 - 140 deg C); regioselective alkylation (5-nitro-isomer); Product distributionMechanism;
参考文献
Rao, A. K. S. Bhujanga; Rao, C. Gundu; Singh, B. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 17 p. 2399 - 2402
