Musatova, I. S.; Elina, A. S.; Solov'eva, N. P.; Polukhina, L. M.; Moskalenko, N. Yu.; Pershin, G. N.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 11 p. 779 - 784
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 11 p. 1307 - 1312
1: Ca(OH)2 / propan-2-ol / 1.) 40-45 deg C, 4 h, 2.) 20-23 deg C, 18 h
2: 97 percent / Br2 / CH2Cl2; dimethylformamide / 3 h / 60 - 65 °C
3: 93 percent / Et3N / acetone / 2.5 h / 35 - 40 °C
4: 93 percent / conc. HCl / 18 h / 22 - 25 °C
5: 97.1 percent / NH3 / ethanol / 18 h / 22 - 25 °C
View Scheme
参考文献
Musatova, I. S.; Elina, A. S.; Solov'eva, N. P.; Polukhina, L. M.; Moskalenko, N. Yu.; Pershin, G. N.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 11 p. 779 - 784
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 11 p. 1307 - 1312
1: 93 percent / Et3N / acetone / 2.5 h / 35 - 40 °C
2: 93 percent / conc. HCl / 18 h / 22 - 25 °C
3: 97.1 percent / NH3 / ethanol / 18 h / 22 - 25 °C
View Scheme
参考文献
Musatova, I. S.; Elina, A. S.; Solov'eva, N. P.; Polukhina, L. M.; Moskalenko, N. Yu.; Pershin, G. N.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 11 p. 779 - 784
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 11 p. 1307 - 1312
1: 93 percent / conc. HCl / 18 h / 22 - 25 °C
2: 97.1 percent / NH3 / ethanol / 18 h / 22 - 25 °C
View Scheme
参考文献
Musatova, I. S.; Elina, A. S.; Solov'eva, N. P.; Polukhina, L. M.; Moskalenko, N. Yu.; Pershin, G. N.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 11 p. 779 - 784
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 11 p. 1307 - 1312
1: 97 percent / Br2 / CH2Cl2; dimethylformamide / 3 h / 60 - 65 °C
2: 93 percent / Et3N / acetone / 2.5 h / 35 - 40 °C
3: 93 percent / conc. HCl / 18 h / 22 - 25 °C
4: 97.1 percent / NH3 / ethanol / 18 h / 22 - 25 °C
View Scheme
参考文献
Musatova, I. S.; Elina, A. S.; Solov'eva, N. P.; Polukhina, L. M.; Moskalenko, N. Yu.; Pershin, G. N.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 11 p. 779 - 784
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 11 p. 1307 - 1312
