(1-甲基-5-硝基-3-苯基-1H-吲哚-2-基)甲醇合成路线 （共 6 条）
反应条件
water in 1,4-dioxane
4 h; Heating;
参考文献
Grinev, A. I.; Krichevskii, E. S.; Romanova, O. B.; Filipenko, T. Ya.; Polezhaeva, A. I.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 635 - 642
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1066 - 1072
反应条件
1: 82 percent / 50percent aq. KOH / acetone / 1 h / 20 °C
2: 95.1 percent / Br2 / 1,2-dichloro-ethane / 1 h / 20 °C / Irradiation
3: 73 percent / dioxane; H2O / 4 h / Heating
View Scheme
参考文献
Grinev, A. I.; Krichevskii, E. S.; Romanova, O. B.; Filipenko, T. Ya.; Polezhaeva, A. I.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 635 - 642
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1066 - 1072
反应条件
1: 95.1 percent / Br2 / 1,2-dichloro-ethane / 1 h / 20 °C / Irradiation
2: 73 percent / dioxane; H2O / 4 h / Heating
View Scheme
参考文献
Grinev, A. I.; Krichevskii, E. S.; Romanova, O. B.; Filipenko, T. Ya.; Polezhaeva, A. I.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 635 - 642
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1066 - 1072
反应条件
1: 70 percent / conc. HCl / acetic acid / 2 h / 80 °C
2: 82 percent / 50percent aq. KOH / acetone / 1 h / 20 °C
3: 95.1 percent / Br2 / 1,2-dichloro-ethane / 1 h / 20 °C / Irradiation
4: 73 percent / dioxane; H2O / 4 h / Heating
View Scheme
参考文献
Grinev, A. I.; Krichevskii, E. S.; Romanova, O. B.; Filipenko, T. Ya.; Polezhaeva, A. I.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 635 - 642
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1066 - 1072
反应条件
chromium(VI) oxide in pyridine
T=20°C; 12 h;
参考文献
Krichevskii, E. S.; Romanova, O. B.; Grinev, A. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , vol. 19, # 12 p. 1302 - 1305
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 12 p. 1648 - 1651
反应条件
1: 70 percent / CrO3 / pyridine / 12 h / 20 °C
2: 37 percent / (NH4)2CO3 / 7 h / 175 - 180 °C
View Scheme
参考文献
Krichevskii, E. S.; Romanova, O. B.; Grinev, A. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , vol. 19, # 12 p. 1302 - 1305
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 12 p. 1648 - 1651
