1: With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 1 h;
2: With boric acid trimethyl ester in tetrahydrofuran; hexane
T=-78 - 20°C;
3: With hydrogenchloride; water in tetrahydrofuran; hexane
参考文献
Bristol-Myers Squibb Company
Patent: US2007/3539 A1, 2007 ;
Location in patent: Page/Page column 81 ;
US 20070003539 A1
