sodium hydroxide in methanol; water 17 h; Heating;

1: 67 percent / potassium carbonate / acetone / 24 h / Heating 2: 60 percent / potassium t-butoxide / tetrahydrofuran / 18 h 3: 81 percent / potassium carbonate / acetone / 48 h / Heating 4: 45 percent / 1N NaOH / methanol; H2O / 17 h / Heating View Scheme

1: conc. H2SO4 / 20 h / Heating 2: 71 percent / sodium methoxide / methanol / 1.5 h / Heating 3: 67 percent / potassium carbonate / acetone / 24 h / Heating 4: 60 percent / potassium t-butoxide / tetrahydrofuran / 18 h 5: 81 percent / potassium carbonate / acetone / 48 h / Heating 6: 45 percent / 1N NaOH / methanol; H2O / 17 h / Heating View Scheme

1: 71 percent / sodium methoxide / methanol / 1.5 h / Heating 2: 67 percent / potassium carbonate / acetone / 24 h / Heating 3: 60 percent / potassium t-butoxide / tetrahydrofuran / 18 h 4: 81 percent / potassium carbonate / acetone / 48 h / Heating 5: 45 percent / 1N NaOH / methanol; H2O / 17 h / Heating View Scheme

1: 81 percent / potassium carbonate / acetone / 48 h / Heating 2: 45 percent / 1N NaOH / methanol; H2O / 17 h / Heating View Scheme

1: 60 percent / potassium t-butoxide / tetrahydrofuran / 18 h 2: 81 percent / potassium carbonate / acetone / 48 h / Heating 3: 45 percent / 1N NaOH / methanol; H2O / 17 h / Heating View Scheme