1: 82 percent / sodium methoxide / methanol / 1.5 h / Heating 2: potassium carbonate / acetone / 24 h / Heating 3: 74 percent / potassium t-butoxide / tetrahydrofuran / 18 h 4: 80 percent / potassium carbonate / acetone / 48 h / Heating 5: 10percent aqueous NaOH / aq. ethanol / 1.5 h / Heating View Scheme

1: 82 percent / sodium methoxide / methanol / 1.5 h / Heating 2: potassium carbonate / acetone / 24 h / Heating 3: 74 percent / potassium t-butoxide / tetrahydrofuran / 18 h 4: 80 percent / potassium carbonate / acetone / 48 h / Heating 5: 72 percent / anhydrous ammonia, lithium / hydrated ferric nitrate / tetrahydrofuran / 16 h View Scheme