4-甲基哌啶-4-羧酸甲酯合成路线 （共 3 条）
反应条件
1: With anhydrous potassium trimethylsilanolate in tetrahydrofuran Heating / reflux; 2: With hydrogenchloride in tetrahydrofuran; 1,4-dioxane T=20°C;
参考文献
ASTRAZENECA AB
Patent: WO2006/73361 A1, 2006 ;
Location in patent: Page/Page column 163 ;
WO 2006/073361 A1
反应条件
1: With anhydrous potassium trimethylsilanolate in tetrahydrofuran Heating / reflux; 2: With hydrogenchloride in 1,4-dioxane T=20°C;
参考文献
ASTRAZENECA AB
Patent: WO2007/8140 A1, 2007 ;
Location in patent: Page/Page column 108 ;
WO 2007/008140 A1
反应条件
hydrogenchloride in tetrahydrofuran; 1,4-dioxane
T=20°C;
参考文献
ASTRAZENECA AB
Patent: WO2007/8140 A1, 2007 ;
Location in patent: Page/Page column 107-108 ;
WO 2007/008140 A1
