(S)-(9CI)-6,7,8,8a-四氢-4-甲基吡咯并[1,2-d][1,2,4]噻嗪-1(2H)-酮合成路线 （共 3 条）
反应条件
hydrazine hydrate in 1,4-dioxane
T=100°C; 4.5 h;
参考文献
Andersen,T.P.; Ghattas,A.B.; Lawesson,S.O.
Tetrahedron, 1983 , vol. 39, p. 3419
反应条件
1: 50 percent / triethylamine / CH2Cl2 / Ambient temperature; 1-2 h
2: 75 percent / 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide / toluene / 3 h / 80 °C
3: 77 percent / 80percent hydrazine hydrate / dioxane / 4.5 h / 100 °C
View Scheme
参考文献
Andersen,T.P.; Ghattas,A.B.; Lawesson,S.O.
Tetrahedron, 1983 , vol. 39, p. 3419
反应条件
1: 75 percent / 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide / toluene / 3 h / 80 °C
2: 77 percent / 80percent hydrazine hydrate / dioxane / 4.5 h / 100 °C
View Scheme
参考文献
Andersen,T.P.; Ghattas,A.B.; Lawesson,S.O.
Tetrahedron, 1983 , vol. 39, p. 3419
