2-(2-溴噻吩-3-基)乙胺合成路线 （共 2 条）
反应条件
1: With bromine; acetic acid
T=0 - 20°C;
2: With sodium hydroxide in water
参考文献
ACTELION PHARMACEUTICALS LTD; BOLLI, Martin; BOSS, Christoph; BROTSCHI, Christine; HEIDMANN, Bibia; SIFFERLEN, Thierry; TRACHSEL, Daniel; WILLIAMS, Jodi T.
Patent: WO2012/114252 A1, 2012 ;
Location in patent: Page/Page column 58 ;
WO 2012/114252 A1
反应条件
1: borane-THF / tetrahydrofuran / 20 °C / Inert atmosphere; Reflux
2: bromine; acetic acid / 0 - 20 °C
View Scheme
参考文献
ACTELION PHARMACEUTICALS LTD; BOLLI, Martin; BOSS, Christoph; BROTSCHI, Christine; HEIDMANN, Bibia; SIFFERLEN, Thierry; TRACHSEL, Daniel; WILLIAMS, Jodi T.
Patent: WO2012/114252 A1, 2012 ;
WO 2012/114252 A1
