反应条件
1: (2-chloro-pyridin-4-yl)-carbamic acid tert-butyl ester With tert.-butyl lithium in tetrahydrofuran; pentane T=-70°C; 2 h; Inert atmosphere; 2: N,N-dimethyl-formamide in tetrahydrofuran; pentane T=-70 - 20°C; 3 h; Inert atmosphere;
参考文献
Bilodeau, Mark T.; Balitza, Adrienne E.; Hoffman, Jacob M.; Manley, Peter J.; Barnett, Stanley F.; Defeo-Jones, Deborah; Haskell, Kathleen; Jones, Raymond E.; Leander, Karen; Robinson, Ronald G.; Smith, Anthony M.; Huber, Hans E.; Hartman, George D.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 11 p. 3178 - 3182