反应条件
1: 2-methyl-5-chlorothiophene With PdCl2(MeCN)2; caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in N,N-dimethyl-formamide T=20°C; Sonogashira coupling; 0.5 h; Inert atmosphere; 2: (Tri-iso-propylsilyl)acetylene in N,N-dimethyl-formamide T=100°C; Sonogashira coupling; 18 h; Inert atmosphere;
参考文献
Zastrow, Marc; Thyagarajan, Sujatha; Ahmed, Saleh A.; Haase, Paul; Seedorff, Sabine; Gelman, Dmitri; Wachtveitl, Josef; Galoppini, Elena; Rueck-Braun, Karola
Chemistry - An Asian Journal, 2010 , vol. 5, # 5 p. 1202 - 1212
