6-(4,4,5,5-三甲基-1,3,2-二氧代硼戊烷-2-基)-3,4-二氢异喹啉-2(1H)-甲酸叔丁酯合成路线 （共 8 条）
反应条件
potassium acetate; 1,1'-bis-(diphenylphosphino)ferrocene; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in 1,4-dioxane T=90°C; 4 h; Inert atmosphere;
参考文献
WO2010/145202 A1, ;
Page/Page column 36-37 ;
WO 2010/145202 A1
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in N,N-dimethyl-formamide T=85°C; 4 h;
参考文献
US2008/171754 A1, ;
Page/Page column 102 ;
US 20080171754 A1
参考文献
US2010/113512 A1, ;
US 20100113512 A1
反应条件
1.1: triethylamine / methanol / 20 °C / Inert atmosphere 2.1: 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.08 h / 20 °C / Inert atmosphere 2.2: 4 h / 90 °C / Inert atmosphere View Scheme
参考文献
WO2010/146105 A1, ;
WO 2010/146105 A1
反应条件
1.1: triethylamine / methanol / 20 °C / Inert atmosphere 2.1: 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 0.08 h / 20 °C / Inert atmosphere 2.2: 4 h / 90 °C / Inert atmosphere View Scheme
参考文献
WO2010/146105 A1, ;
WO 2010/146105 A1
反应条件
1: 2-(3-methoxy-phenyl)-ethylamine 2: triethylamine / dichloromethane; ethyl acetate; tetrahydrofuran 3: triethylamine; Tf2O / dichloromethane View Scheme
反应条件
1: triethylamine / dichloromethane; ethyl acetate; tetrahydrofuran 2: triethylamine; Tf2O / dichloromethane View Scheme
反应条件
1: triethylamine; Tf2O / dichloromethane View Scheme
