5-(间甲苯)异噁唑-3-羧酸乙酯合成路线 （共 3 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; toluene
T=20°C; 2 h;
参考文献
ASTRAZENECA AB
Patent: WO2008/41075 A1, 2008 ;
Location in patent: Page/Page column 40 ;
WO 2008/041075 A1
反应条件
hydroxylamine hydrochloride in ethanol
3 h; Reflux;
参考文献
Akbarzadeh, Tahmineh; Rafinejad, Ali; Mollaghasem, Javad Malekian; Safavi, Maliheh; Fallah-Tafti, Asal; Pordeli, Mahboobeh; Ardestani, Sussan Kabudanian; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2012 , vol. 345, # 5 p. 386 - 392
反应条件
triethylamine
T=20°C;
参考文献
Pieroni, Marco; Lilienkampf, Annamaria; Wang, Yuehong; Wan, Baojie; Cho, Sanghyun; Franzblau, Scott G.; Kozikowski, Alan P.
ChemMedChem, 2010 , vol. 5, # 10 p. 1667 - 1672
