5,5,5-三氟-2,4-二氧代-戊酸乙酯合成路线 （共 3 条）
反应条件
pyridine in diethyl ether 48 h; Ambient temperature;
参考文献
Bessiere, J. M.; Boutevin, B.; El Bachiri, A.; El Harfi, A.
Journal of Fluorine Chemistry, 1993 , vol. 65, # 1-2 p. 91 - 96
反应条件
1: With hydroxylamine hydrochloride in ethanol
2 h; Reflux;
2: With pyridine; thionyl chloride in toluene
0.5 h; Reflux;
参考文献
Hebeisen, Paul; Matile, Hugues; Roever, Stephan; Wright, Matthew; Jensen, Sannah Zoffmann
Patent: US2012/65212 A1, 2012 ;
Location in patent: Page/Page column 31 ;
US 20120065212 A1
反应条件
1: in ethanol
2 h; Reflux;
2: With pyridine; thionyl chloride in toluene
0.5 h; Reflux;
参考文献
F. HOFFMANN-LA ROCHE AG; HEBEISEN, Paul; ZOFFMANN JENSEN, Sannah; MATILE, Hugues; ROEVER, Stephan; WRIGHT, Matthew
Patent: WO2012/32018 A1, 2012 ;
Location in patent: Page/Page column 66 ;
WO 2012/032018 A1
