4-(5-乙酰基-2-噻吩基)苯甲醛合成路线 (共 2 条)
反应条件
potassium phosphate; (1,2,3,4,5-pentaphenylferrocen-1'-yl)-di-tert-butylphosphine; bis(dibenzylideneacetone)-palladium(0) in 1,4-dioxane; water
T=40°C; Suzuki-Miyaura cross-coupling; 18 h; Inert atmosphere;
参考文献
Robbins, Daniel W.; Hartwig, John F.
Organic Letters, 2012 , vol. 14, # 16 p. 4266 - 4269
反应条件
1: bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 4,4'-di-tert-butyl-2,2'-dipyridyl / tetrahydrofuran / 18 h / 80 °C / Inert atmosphere
2: potassium phosphate; (1,2,3,4,5-pentaphenylferrocen-1'-yl)-di-tert-butylphosphine; bis(dibenzylideneacetone)-palladium(0) / 1,4-dioxane; water / 18 h / 40 °C / Inert atmosphere
View Scheme
参考文献
Robbins, Daniel W.; Hartwig, John F.
Organic Letters, 2012 , vol. 14, # 16 p. 4266 - 4269