反应条件
1: 1-bromo-4-methylsulfanyl benzene With chloro-trimethyl-silane; tributoxyborane; magnesium; ethylene dibromide; lithium chloride in tetrahydrofuran
T=25°C; 1 h; Inert atmosphere;
2: 5-Bromo-1H-indole With 1,1'-bis-(diphenylphosphino)ferrocene; caesium carbonate; palladium dichloride in tetrahydrofuran; ethanol; N,N-dimethyl-formamide
T=65°C; Suzuki-Miyaura cross coupling reaction; 6 h; Inert atmosphere;
参考文献
Haag, Benjamin A.; Saemann, Christoph; Jana, Anukul; Knochel, Paul
Angewandte Chemie - International Edition, 2011 , vol. 50, # 32 p. 7290 - 7294