3-羟基-5-硝基噻吩-2-羧酸甲酯合成路线 （共 2 条）
反应条件
sulfuric acid; nitric acid T=-10 - 0°C;
参考文献
Journal of Chemical Research, Miniprint, , # 10 p. 1001 - 1023
反应条件
1: With polymer supported triphenylphosphine; diethylazodicarboxylate in dichloromethane
T=0 - 20°C; 21.25 h;
2: With hydrogenchloride in 1,4-dioxane
T=20°C; 3 h;
参考文献
Hornberger, Keith R.; Badiang, Jennifer G.; Salovich, James M.; Kuntz, Kevin W.; Emmitte, Kyle A.; Cheung, Mui
Tetrahedron Letters, 2008 , vol. 49, # 44 p. 6348 - 6351
