7-苄基-3-硫杂-7-氮杂双环[3.3.1]壬烷合成路线 (共 3 条)
反应条件
potassium hydroxide; hydrazine hydrate; 1,2-bis-(2-hydroxyethoxy)-ethane
T=145 - 150°C; 4 h;
参考文献
Bailey III; Berlin; Holt; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 758 - 767
反应条件
1: 38 percent / CH3COOH / methanol / 5 h / Heating
2: N2H4*H2O, triethylene glycol, KOH / 4 h / 145 - 150 °C
View Scheme
参考文献
Bailey III; Berlin; Holt; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 758 - 767
反应条件
1: 38 percent / CH3COOH / methanol / 5 h / Heating
2: N2H4*H2O, triethylene glycol, KOH / 4 h / 145 - 150 °C
View Scheme
参考文献
Bailey III; Berlin; Holt; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 758 - 767