3-羟基-3,3-二苯基丙酸乙酯合成路线 （共 18 条）
反应条件
triethylsilane; boron trifluoride diethyl etherate in dichloromethane
T=0°C; 0.5 h; further temperature; Yield given. Yields of byproduct given;
参考文献
Orfanopoulos, Michael; Smonou, Ioulia
Synthetic Communications, 1988 , vol. 18, # 8 p. 833 - 840
反应条件
hydrazine hydrate in methanol
3 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2810 - 2819
反应条件
ethylmagnesium bromide
参考文献
Petjunin; Pesis
Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 979;engl.Ausg.S.1033
反应条件
in tetrahydrofuran; diethyl ether
Grignard reaction; reduction; 0.5 h; Heating;
参考文献
Olah, George A.; Reddy, V. Prakash; Rasul, Golam; Prakash, G. K. Surya
Journal of the American Chemical Society, 1999 , vol. 121, # 43 p. 9994 - 9998
反应条件
1: p-toluenesulfonic acid / benzene / 5 h / Heating
2: diisobutylaluminium hydride / toluene / 16 h / Ambient temperature
View Scheme
参考文献
Heilmann; Glenat
Bulletin de la Societe Chimique de France, 1955 , p. 1586,1590
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C
2: iodobenzene dichloride; sodium azide / ethyl acetate / 12 h / 0 - 80 °C / |Inert atmosphere
View Scheme
参考文献
He, Tian; Gao, Wen-Chao; Wang, Wei-Kun; Zhang, Chi
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 5 p. 1113 - 1118
反应条件
formic acid
T=145 - 150°C; man kocht das Reaktionsprodukt mit verd. Natronlauge;
参考文献
Rupe
Justus Liebigs Annalen der Chemie, 1913 , vol. 395, p. 138
反应条件
T=145 - 150°C; folgendes Verseifen mit Natronlauge;
参考文献
Rupe
Justus Liebigs Annalen der Chemie, 1913 , vol. 395, p. 138
