3-氯-4-氧代-哌啶-1-羧酸叔丁酯合成路线 （共 6 条）
反应条件
in tetrahydrofuran T=-60°C; 1 h;
参考文献
Wender, Paul A.; White, Alan W.
Tetrahedron, 1983 , vol. 39, # 22 p. 3767 - 3776
反应条件
1: 51 percent / molecular sieves 4 Angstroem / ethanol 2: 40 percent / LiAlH4 / diethyl ether View Scheme
参考文献
Haginoya, Noriyasu; Kobayashi, Syozo; Komoriya, Satoshi; Hirokawa, Yumiko; Furugori, Taketoshi; Nagahara, Takayasu
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 11 p. 2935 - 2939
反应条件
1: 51 percent / molecular sieves 4 Angstroem / ethanol 2: aq. NaOH View Scheme
参考文献
Haginoya, Noriyasu; Kobayashi, Syozo; Komoriya, Satoshi; Hirokawa, Yumiko; Furugori, Taketoshi; Nagahara, Takayasu
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 11 p. 2935 - 2939
反应条件
1: 58 percent / tetrahydrofuran / 1 h / -60 °C 2: 48 percent / dimethylformamide; triethylamine; pyridine / 1 h / 90 °C 3: 77 percent / MeLi / tetrahydrofuran; diethyl ether / 1 h / Ambient temperature View Scheme
参考文献
Wender, Paul A.; White, Alan W.
Tetrahedron, 1983 , vol. 39, # 22 p. 3767 - 3776
反应条件
1: 51 percent / molecular sieves 4 Angstroem / ethanol 2: aq. NaOH View Scheme
参考文献
Haginoya, Noriyasu; Kobayashi, Syozo; Komoriya, Satoshi; Hirokawa, Yumiko; Furugori, Taketoshi; Nagahara, Takayasu
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 11 p. 2935 - 2939
反应条件
N-chloro-succinimide in acetone
T=0°C; 1 h;
参考文献
Wender, Paul A.; White, Alan W.
Tetrahedron, 1983 , vol. 39, # 22 p. 3767 - 3776
