6-硝基硫代苯并二氢吡喃-4-酮合成路线 （共 3 条）
反应条件
1: aqueous hydrochloric acid; tin View Scheme
参考文献
Song, Jiangli; Jones, Lindsay M.; Kumar, G. D. Kishore; Conner, Elizabeth S.; Bayeh, Liela; Chavarria, Gustavo E.; Charlton-Sevcik, Amanda K.; Chen, Shen-En; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 450 - 453
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 60 °C / Inert atmosphere
1.2: 1.5 h / 60 °C / Inert atmosphere
2.1: polyphosphonic acid / 0.5 h / 100 °C
View Scheme
参考文献
MERCK SERONO S.A.; GAILLARD, Pascale; JEANCLAUDE-ETTER, Isabelle; POMEL, Vincent; SEBILLE, Eric; JEYAPRAKASHNARAYANAN, Seenisamy; MUZERELLE, Mathilde
Patent: WO2011/58149 A1, 2011 ;
WO 2011/058149 A1
反应条件
1: alkaline water
2: phosphorus (V)-oxide; concentrated sulfuric acid
View Scheme
参考文献
Bellavita
Gazzetta Chimica Italiana, 1940 , vol. 70, p. 584,592
