反应条件
1: 5 percent / NaCNBH3 / 1) RT, 2 h, 2) 55 deg C, 1.5 h, 3) RT, overnight
2: conc. HCl, glacial HOAc / Heating
3: 55 percent / 20percent Pd-C / various solvent(s) / 21 h / 150 °C
View Scheme
参考文献
Rauckman; Tidwell; Johnson; Roth
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1927 - 1935