potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate in acetonitrile T=20°C; 0.333333 h;

1: 82 percent / aq. NH3 / Ambient temperature 2: 80 percent / POCl3 / pyridine / 1.5 h / 5 - 10 °C 3: 94 percent / K2CO3 / tetrabutylammonium hydrogen sulfate / acetonitrile / 0.33 h / 20 °C View Scheme

1: 80 percent / POCl3 / pyridine / 1.5 h / 5 - 10 °C 2: 94 percent / K2CO3 / tetrabutylammonium hydrogen sulfate / acetonitrile / 0.33 h / 20 °C View Scheme