9-氨基-N-[3-(二甲基氨基)丙基]-4-吖啶甲酰胺合成路线 （共 4 条）
反应条件
1: SOCl2, DMF / Heating
2: CH2Cl2 / 30 °C
3: 50 °C
4: NH3 gas / various solvent(s) / 115 °C
View Scheme
参考文献
Atwell; Cain; Baguley; Finlay; Denny
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1481 - 1485
反应条件
1: CH2Cl2 / 30 °C
2: 50 °C
3: NH3 gas / various solvent(s) / 115 °C
View Scheme
参考文献
Atwell; Cain; Baguley; Finlay; Denny
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1481 - 1485
反应条件
1: 83 percent / conc. H2SO4 / 4 h / 100 °C
2: SOCl2, DMF / Heating
3: CH2Cl2 / 30 °C
4: 50 °C
5: NH3 gas / various solvent(s) / 115 °C
View Scheme
参考文献
Atwell; Cain; Baguley; Finlay; Denny
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1481 - 1485
反应条件
1: 50 °C
2: NH3 gas / various solvent(s) / 115 °C
View Scheme
参考文献
Atwell; Cain; Baguley; Finlay; Denny
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1481 - 1485
