反应条件
1: cuprous iodide, N-ethylmorpholine / benzene; various solvent(s) / 1 h / 120 °C
2: 91 percent / polyphosphoric acid / 1 h / 120 °C
3: SOCl2 / 1 h / Heating
4: CH2Cl2 / 0.5 h / 20 °C
5: NH3(g) / various solvent(s) / 0.25 h / 110 - 120 °C
View Scheme
参考文献
Rewcastle, Gordon W.; Atwell, Graham J.; Chambers, David; Baguley, Bruce C.; Denny, William A.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 4 p. 472 - 477
