4-羟基-2-甲基苯并呋喃-6-羧酸乙酯合成路线 (共 2 条)
反应条件
potassium carbonate in ethanol; hexane; dichloromethane; toluene
参考文献
Pfizer Inc
Patent: US2010/234285 A1, 2010 ;
US 20100234285 A1
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine in ethylene glycol dimethyl ether
Sonogashira coupling;
参考文献
Berliner, Martin A.; Cordi, Eric M.; Dunetz, Joshua R.; Price, Kristin E.
Organic Process Research and Development, 2010 , vol. 14, # 1 p. 180 - 187