N,N-dicyclohexylmethylamine; Pd0(tris(tert-butyl)phosphine)2 in water; N,N-dimethyl-formamide T=50°C; 96 h;

1: 4,4,5,5-tetramethyl-2-[3-(tetrahydro-2H-pyran-2-yloxy)prop-(1E)-enyl]-1,3,2-dioxaborolane With potassium carbonate; 1,1'-bis(di-tert-butylphosphino)ferrocene palladium dichloride in water; acetonitrile T=20°C; 0.0833333 h; 2: N-(5-bromo-4-(4-fluorophenyl)-6-isopropylpyriinidin-2-yl)-N-methylmethanesulfonamide in water; acetonitrile T=77°C; 5 h; Heating / reflux; 3: With water; sodium hydrogencarbonate; hydrogenchloride more than 3 stages;