5-溴-4-(4-氟苯基)-6-异丙基嘧啶-2-醇合成路线 （共 2 条）
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide
T=-8.5 - 20°C; 4.16667 h;
参考文献
Butters, Michael; Lenger, Steven Robert; Murray, Paul Michael; Snape, Evan William
Patent: US2008/207903 A1, 2008 ;
Location in patent: Page/Page column 17 ;
反应条件
1: With trichlorophosphate
T=90°C; 2.5 h;
2: With sodium hydrogencarbonate in water; ethyl acetate
Neutrality;
参考文献
ASTRAZENECA UK LIMITED
Patent: WO2007/7119 A1, 2007 ;
Location in patent: Page/Page column 6; 23 ;
WO 2007/007119 A1
