7-溴-2,2-二甲基-2H-吡啶并[3,2-B]-1,4-恶嗪-3(4H)-酮合成路线 （共 2 条）
反应条件
potassium carbonate in acetone
18 h; Heating / reflux;
参考文献
AFFINIUM PHARMACEUTICALS, INC.
Patent: WO2007/53131 A2, 2007 ;
Location in patent: Page/Page column 130 ;
WO 2007/053131 A2
反应条件
1: 2-amino-3-hydroxy-5-bromopyridine With sodium hydride in N,N-dimethyl-formamide
T=20°C; 0.5 h;
2: ethyl 2-bromo-2-methyl propionate in N,N-dimethyl-formamide
T=20 - 80°C; 3.33333 h;
参考文献
TANABE SEIYAKU CO., LTD.
Patent: WO2007/89034 A1, 2007 ;
Location in patent: Page/Page column 77 ;
WO 2007/089034 A1
