1: 96 percent / pyridine / 24 h / 70 °C 2: 100 percent / pyridine / 40 h / Ambient temperature View Scheme

1: Et3N / toluene / 3 h / Heating 2: pyridine View Scheme

pyridine 40 h; Ambient temperature;

pyridine

1: H2, CaCO3 / 10percent Pd/C / CHCl3 / 18 h / 40 °C / 1034.3 Torr 2: 1.) Et3N, 2.) Et3N, water / 1.) diethyl ether, RT, 5 h, 2.) diethyl ether, reflux, 2 h 3: CHCl3; propan-2-ol; dimethylformamide / 12 h / 50 °C View Scheme