反应条件
1: 4-bromo-pyridine With n-butyllithium in diethyl ether; hexane
T=-78°C; 0.5 h;
2: 4,6-dichloro-pyrimidine in diethyl ether; hexane
T=-30 - 0°C; 1 h;
3: With acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone in diethyl ether; hexane; water
0.5 h;
参考文献
Erickson, Shawn David; Baldwin, John J.; Dolle III, Roland Ellwood; Inglese, James; Ohlmeyer, Michael H.J.; Ho, Koc-Kan; Bohnstedt, Adolph C.; Kultgen, Steven G.; Conti, Paolo Giovanni Martino; Leysen, Dirk; van der Louw, Jaap
Patent: US2004/87601 A1, 2004 ;
Location in patent: Page 10-11 ;
US 20040087601 A1
