1-苯基-3-三甲基硅烷-2-丙炔-1-醇合成路线 （共 25 条）
反应条件
1: potassium carbonate / methanol / 2 h / 20 °C 2: manganese(IV) oxide / dichloromethane / 0 - 20 °C View Scheme
参考文献
Ge, Guang-Cun; Mo, Dong-Liang; Ding, Chang-Hua; Dai, Li-Xin; Hou, Xue-Long
Organic Letters, 2012 , vol. 14, # 22 p. 5756 - 5759
反应条件
potassium carbonate in methanol T=20°C; 1 h; Inert atmosphere;
参考文献
Wang, Ya-Hui; Liu, Heng; Zhu, Li-Li; Li, Xiao-Xiao; Chen, Zili
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 5 p. 707 - 712
反应条件
potassium tert-butylate in toluene T=100°C; 4 h; Inert atmosphere;
参考文献
Wang, Xu; Pan, Ying-Ming; Huang, Xiao-Chao; Mao, Zhong-Yuan; Wang, Heng-Shan
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 13 p. 2028 - 2032
反应条件
1.1: 90 percent / potassium hexafluorophosphate / (dppm)Re(O)Cl3 / nitromethane / Heating 2.1: dicyclohexylborane / tetrahydrofuran / 1.5 h / 0 °C 2.2: sodium hydroxide; hydrogen peroxide / tetrahydrofuran; methanol; H2O View Scheme
参考文献
Kennedy-Smith, Joshua J.; Young, Lauren A.; Toste, F. Dean
Organic Letters, 2004 , vol. 6, # 8 p. 1325 - 1327
反应条件
Iron (III) nitrate nonahydrate; 2,2,6,6-tetramethyl-piperidine-N-oxyl; oxygen; sodium chloride in 1,2-dichloro-ethane T=25°C; P=760.051 Torr; 4 h;
参考文献
Ma, Shengming; Liu, Jinxian; Li, Suhua; Chen, Bo; Cheng, Jiajia; Kuang, Jinqiang; Liu, Yu; Wan, Baoqiang; Wang, Yuli; Ye, Juntao; Yu, Qiong; Yuan, Weiming; Yu, Shichao
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 6 p. 1005 - 1017
反应条件
1: With silica gel in dichloromethane 2: 0.0833333 h; Microwave irradiationNeat (no solvent);
参考文献
Chen, Qing-Zhen; Ding, Zong-Cang; Ma, Yan-Li; Wang, Zhen-Dong; Zhan, Zhuang-Ping
Heterocycles, 2012 , vol. 85, # 8 p. 1891 - 1896
反应条件
1: trimethylsilylacetylene With n-butyllithium in tetrahydrofuran
T=0°C; 1 h;
2: benzaldehyde in tetrahydrofuran
T=0°C; 1 h;
参考文献
Yan, Wuming; Wang, Qiaoyi; Chen, Yunfeng; Petersen, Jeffrey L.; Shi, Xiaodong
Organic Letters, 2010 , vol. 12, # 15 p. 3308 - 3311
反应条件
1: benzoic acid ethyl ester With LDBBA in tetrahydrofuran; hexane
T=0°C;
2: LiTMS-acetylene in tetrahydrofuran; hexane
T=20°C;
参考文献
Chae, Min Jung; Jeon, Ah Ram; Livinghouse, Tom; An, Duk Keun
Chemical Communications, 2011 , vol. 47, # 11 p. 3281 - 3283
反应条件
1: trans-1,2-dichloroethylene With n-butyllithium in tetrahydrofuran; hexane
T=0°C;
2: benzaldehyde in tetrahydrofuran; hexane
T=0°C;
3: trimethylsilyl trifluoromethanesulfonate Further stages;
参考文献
Nagaki, Aiichiro; Matsuo, Chika; Kim, Songhee; Saito, Kodai; Miyazaki, Atsuo; Yoshida, Jun-Ichi
Angewandte Chemie - International Edition, 2012 , vol. 51, # 13 p. 3245 - 3248
反应条件
1: 3-hydroxy-3-phenyl-prop-1-yne With n-butyllithium in tetrahydrofuran; hexane
T=-78 - 22°C;
2: chloro-trimethyl-silane in tetrahydrofuran; hexane
T=-78 - 22°C; Further stages.;
参考文献
Kacprzynski, Monica A.; Kazane, Stephanie A.; May, Tricia L.; Hoveyda, Amir H.
Organic Letters, 2007 , vol. 9, # 16 p. 3187 - 3190
