1: bis(4-chlorophenyl)borinic acid With sodium hydroxide in tetrahydrofuran; water T=20°C; 1 h; 2: With triphenylphosphine in tetrahydrofuran; water T=20°C; 0.5 h; 3: 1-Bromo-2-aminobenzene With hydrogenchloride; palladium dichloride in tetrahydrofuran; water T=100°C; P=2625.26 Torr; 12 h;

water; bromine

(i) Ph2NBCl2, Et2O, benzene, (ii) aq. HCl; Multistep reaction;

hydrogenchloride in tetrahydrofuran

water byproducts: BrMgOH;

in tetrahydrofuran T=11 - 20°C; 3 h;

diethyl ether

暂无反应条件数据

1: bis(4-chlorophenyl)borinic acid With KHF2 in methanol 2: para-bromoacetophenone With sodium carbonate; triphenylphosphine; palladium diacetate in 2-methoxy-ethanol Suzuki-Miyaura reaction; Heating;

1: bis(4-chlorophenyl)borinic acid With sodium hydroxide in 1,4-dioxane; water T=18 - 22°C; 1.1 h; 2: With triphenylphosphine in 1,4-dioxane; water T=18 - 22°C; 0.5 h; 3: 1-chloro-2-nitro-benzene With dichloro bis(acetonitrile) palladium(II) in 1,4-dioxane; water T=100°C; P=2775.28 Torr; 11.5 h; Product distribution / selectivity;